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Timeline of antibiotics : ウィキペディア英語版
Timeline of antibiotics

This is the timeline of antimicrobial (anti-infective) therapy.
The years show when a given drug was released onto the pharmaceutical
market. This is not a timeline of the development of the antibiotics themselves.
* 1911 - Arsphenamine aka Salvarsan
* 1912 - Neosalvarsan
* 1935 - Prontosil (an oral precursor to sulfanilimide), the first sulfonamide
* 1936 - Sulfanilimide
* 1938 - Sulfapyridine (M&B 693)
* 1939 - sulfacetamide
* 1940 - sulfamethizole
* 1942 - benzylpenicillin, the first penicillin
* 1942 - gramicidin S, the first peptide antibiotic
* 1942 - sulfadimidine
* 1943 - sulfamerazine
* 1944 - streptomycin, the first aminoglycoside
* 1947 - sulfadiazine
* 1948 - chlortetracycline, the first tetracycline
* 1949 - chloramphenicol, the first amphenicol
* 1949 - neomycin
* 1950 - oxytetracycline
* 1950 - penicillin G procaine
* 1952 - erythromycin, the first macrolide
* 1954 - benzathine penicillin
* 1955 - spiramycin
* 1955 - tetracycline
* 1955 - thiamphenicol
* 1955 - vancomycin, the first glycopeptide
* 1956 - phenoxymethylpenicillin
* 1958 - colistin, the first polymyxin
* 1958 - demeclocycline
* 1959 - virginiamycin
* 1960 - methicillin
* 1960 - metronidazole, the first nitroimidazole
* 1961 - ampicillin
* 1961 - spectinomycin
* 1961 - sulfamethoxazole
* 1961 - trimethoprim, the first dihydrofolate reductase inhibitor
* 1962 - cloxacillin
* 1962 - fusidic acid
* 1963 - fusafungine
* 1963 - lymecycline
* 1964 - gentamicin
* 1964 - Cefalotin, the first cephalosporin
* 1966 - doxycycline
* 1967 - carbenicillin
* 1967 - rifampicin
* 1967 - Nalidixic acid, the first quinolone
* 1968 - clindamycin, the second lincosamide
* 1970 - cefalexin
* 1971 - cefazolin
* 1971 - pivampicillin
* 1971 - tinidazole
* 1972 - amoxicillin
* 1972 - cefradine
* 1972 - minocycline
* 1972 - pristinamycin
* 1973 - fosfomycin
* 1974 - talampicillin
* 1975 - tobramycin
* 1975 - bacampicillin
* 1975 - ticarcillin
* 1976 - amikacin
* 1977 - azlocillin
* 1977 - cefadroxil
* 1977 - cefamandole
* 1977 - cefoxitin
* 1977 - cefuroxime
* 1977 - mezlocillin
* 1977 - pivmecillinam
==From 1978==

* 1979 - cefaclor
* 1980 - cefmetazole
* 1980 - cefotaxime
* 1980 - cefsulodin
* 1980 - piperacillin
* 1981 - co-amoxiclav (amoxicillin/clavulanic acid)
* 1981 - cefoperazone
* 1981 - cefotiam
* 1981 - cefsulodin
* 1981 - latamoxef
* 1981 - netilmicin
* 1982 - ceftriaxone
* 1982 - micronomicin
* 1983 - cefmenoxime
* 1983 - ceftazidime
* 1983 - ceftizoxime
* 1983 - norfloxacin
* 1984 - cefonicid
* 1984 - cefotetan
* 1984 - temocillin
* 1985 - cefpiramide
* 1985 - imipenem/cilastatin, the first carbapenem
* 1985 - ofloxacin
* 1986 - mupirocin
* 1986 - aztreonam
* 1986 - cefoperazone/sulbactam
* 1986 - co-ticarclav (ticarcillin/clavulanic acid)
* 1987 - ampicillin/sulbactam
* 1987 - cefixime
* 1987 - roxithromycin
* 1987 - sultamicillin
* 1987 - ciprofloxacin, the first 2nd-gen fluoroquinolone
* 1987 - rifaximin, the first ansamycin
* 1988 - azithromycin
* 1988 - flomoxef
* 1988 - isepamycin
* 1988 - midecamycin
* 1988 - rifapentine
* 1988 - teicoplanin
* 1989 - cefpodoxime
* 1989 - enrofloxacin
* 1989 - lomefloxacin
* 1989 - moxifloxacin
* 1990 - arbekacin
* 1990 - cefozidime
* 1990 - clarithromycin
* 1991 - cefdinir
* 1992 - cefetamet
* 1992 - cefpirome
* 1992 - cefprozil
* 1992 - ceftibuten
* 1992 - fleroxacin
* 1992 - loracarbef
* 1992 - piperacillin/tazobactam
* 1992 - rufloxacin
* 1993 - brodimoprim
* 1993 - dirithromycin
* 1993 - levofloxacin
* 1993 - nadifloxacin
* 1993 - panipenem/betamipron
* 1993 - sparfloxacin
* 1994 - cefepime
* 1999 - quinupristin/dalfopristin
* 2000 - linezolid, the first oxazolidinone
* 2001 - telithromycin, the first ketolide
* 2003 - daptomycin
* 2005 - tigecycline
* 2005 - doripenem
* 2009 - telavancin, the first Lipoglycopeptide
* 2010 - ceftaroline
* 2011 - fidaxomicin
* 2012 - bedaquiline
* 2013 - telavancin
* 2014 - tedizolid
* 2014 - dalbavancin
* 2015 - ceftolozane/tazobactam

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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